Cutting right to the chase: it's a big-ass Warhammer 40K thing. I know zero about the setting and care even less.
What I do care about is that fans of the classic Dune boardgame are now down to just the remaining "small" mystery box if they're hoping to hear any news concerning Dune: Imperium / Twilight: Dune / Dune: Dinosaur Planet in 2009 or early 2010.
My gut feeling is that the small box will not be the new Dune game. Considering the original announcement came in the summer of 2007, I'm beginning to lose faith that FFG will ever get this game to market.